Brain Tumors

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Brain Tumors

The causes of brain tumors are not fully understood, but risk factors include radiation exposure, genetic disorders, a family history of tumors, diseases that affect the immune system, stress, and exposure to various environmental carcinogens.

It is thought that brain tumors occur as a result of damage or improper function of specific genes located in the chromosomes of cells. This damage or dysfunction in genes can occur as a result of various environmental factors, as well as being congenital due to genetic disorders in some individuals. When the mechanisms that control cell division are damaged, cells begin to divide and multiply uncontrollably and eventually form an abnormal mass, that is, a tumor. A rapidly growing tumor requires more oxygen and nutrients than normal tissue. Therefore, the tumor produces substances that stimulate the growth of blood vessels to meet its own needs for nourishment and oxygen.

Brain tumors are divided into two main groups: primary (originating from brain tissue) and metastatic (spread to the brain from elsewhere in the body). Primary brain tumors arise either from the brain tissue or the tissues surrounding it. Additionally, while metastatic tumors are considered malignant (cancerous), primary brain tumors can be malignant or benign (non-cancerous).

The symptoms of brain tumors vary greatly depending on the location in the brain. Accompanying symptoms are usually headache that is more severe in the morning, nausea, vomiting, epileptic seizures, personality changes, speech disturbances, hearing impairments, balance disturbances, numbness or weakness in parts of the body, vision problems, and consciousness impairment.

Various imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI) are used for diagnosis.

Treatment methods for brain tumors may involve microsurgery, radiosurgery (gamma knife, cyber knife), radiotherapy (standard external radiotherapy, IMRT, 3DCRT, proton beam therapy), and chemotherapy (drug therapy), either alone or in combination, depending on the tumor type (primary or metastatic, benign or malignant).Each treatment method has its own specific risks and side effects. In addition to these treatment methods, there are also emerging techniques still in the research phase, such as immunotherapy and gene therapy.

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